Allergy Complex
Product ID: ES509
Description:
THE KEY INGREDIENTS FOR NORMALIZING THE BODY'S HISTAMINE RESPONSE.
Quercetin, nettles,zinc, bromelain, licorice, and vitamin c are all well known allergy mediators.
Recommended 1-3 tablets per day.
Price: $8.10
Price shown is for one item per day for 30 days.
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| Vitamin C | 166 mg | 276 |
| Magnesium | 13.3 mg | 13.3 |
| Zinc | 10 mg | 23 |
| Vitamin B6 | 6.6 mg | 333 |
| Bromelain | 166 mg | ** |
| Quercetin | 266 mg | ** |
| Licorice Extract | 66 mg | ** |
| Pantothenate | 33 mg | 333 |
| Nettle Extract | 166 mg | ** |
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* Percent Daily Values (DV) are based on a 2000 calorie diet. ** Daily value not established |
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Consult with your doctor before taking any nutritional supplements. These statements
have not been evaluated by the Food and Drug Administration. This information and product
is not intended to diagnose, treat, cure or prevent any disease. It is provided for educational
purposes only and is not intended as medical advice. If you have any concerns you should consult
with an appropriate health professional.
Details:
Ingredient Details
In human cell culture studies, Quercetin has been shown to inhibit histamine release.
Quercetin has a strong affinity for mast cells and basophils. It tends to stabilize their cell membranes, preventing them from spilling their pro-inflammatory, allergy-symptom-causing load of histamine/serotonin into the surrounding blood and tissue in response to the IgE antibody. And without the release of these potent inflammatory mediators, the familiar misery of allergies simply will not occur, even though you've inhaled the pollen, animal hair, or whatever normally triggers allergy attacks.
Asthma is an allergic inflammation involving the lungs. During an asthma attack (which can be triggered by air- or food-borne pollen, dust, animal hair, chemicals, etc.), the millions of tiny air sacs within the lungs are constricted, seriously impairing breathing and causing a feeling of tightness in the chest. In addition to IgE-released histamine, the primary biochemical cause of the asthmatic symptoms is a group of fatty acid derivatives called leukotrienes (LTs). These asthma-causing LTs are made from arachidonic acid (a key fatty acid constituent of many cell membranes) by the action of two enzymes - phospholipase A2 and lipoxygenase. Quercetin is known to be a powerful inhibitor of both these enzymes. Thus it prevents the formation of asthma-causing LTs, even when the IgE antibody (formed in response to inhaled or swallowed allergens) is present in the lungs to stimulate LT Production and release. Since quercetin suppresses the release and/or production of the two primary inflammatory mediators–histamine and leukotrienes–that cause the actual symptoms of asthma, its potential benefit in the prevention and treatment of asthma is evident.
Quercetin is a safe, nontoxic substance. A report by I. Hirono et al in Cancer Letters (1981), for example, found no evidence of toxicity or carcinogenicity in rats, even when quercetin made up 10 percent of their total dietary intake.
Unfortunately, quercetin is barely soluble in water, so poor dietary absorption may limit its efficacy. Because of this, it has been suggested that quercetin be taken in combination with bromelain to improve its absorption. Bromelain is a natural, protein-digesting enzyme derived from pineapples. It has been used "to increase absorption of compounds, including antibiotics. Also, bromelain has powerful anti-inflammatory properties that synergize with quercetin. Bromelain inhibits several other common inflammatory mediators, including bradykinin and fibrin. It's widely used in sports medicine to reduce the pain and swelling of bruises, sprains, muscle tears, etc., for this reason.
Quercetin and Cancer
Quercetin has anti-tumor potential in laboratory studies, and has potential to be useful in various cancers including pancreatic cancer, however human trials are difficult to find.
Quercetin and viral illness
Quercetin, a naturally occurring, powerful antioxidant found in red grapes, red wine, red apples, green tea and broccoli, appears to be one of the first plant compound proven in a double-blind, randomized, placebo-controlled clinical trial to reduce susceptibility to viral illnesses. Dr. David Nieman, a professor at Appalachian State University was the researcher and presented his findings at the southeastern regional meeting of the American College of Sports Medicine in Charlotte, N.C. Participants in the study -- long-distance cyclists -- ingested 1,000 milligrams of pure quercetin, combined with vitamin C and niacin.
In a double-blind, randomized study during the peak season for allergic rhinitis, an extract of the herb nettle leaf (Urtica dioica) was compared to a placebo. Ninety eight participants were given 1300 mg capsules of nettle leaf or placebo and were advised to take two capsules when symptoms began and continue for seven days.
Overall assessment ratings of nettle leaf were higher than placebo, and patients reported a slight reduction in symptoms of hayfever, including sneezing and itchy eyes. This is the only research study that has been conducted on nettle leaf for allergic rhinitis, however, it has a long history of traditional use for allergies.
Licorice (Glycyrrhiza glabra):
Habitual use of licorice can result in a loss of potassium, and it may be necessary to supplement the diet or increase the consumption of potassium-rich foods. Another consideration is that the habitual intake of licorice can promote the retention of sodium
In human cell culture studies, Quercetin has been shown to inhibit histamine release.
Quercetin has a strong affinity for mast cells and basophils. It tends to stabilize their cell membranes, preventing them from spilling their pro-inflammatory, allergy-symptom-causing load of histamine/serotonin into the surrounding blood and tissue in response to the IgE antibody. And without the release of these potent inflammatory mediators, the familiar misery of allergies simply will not occur, even though you've inhaled the pollen, animal hair, or whatever normally triggers allergy attacks.
Asthma is an allergic inflammation involving the lungs. During an asthma attack (which can be triggered by air- or food-borne pollen, dust, animal hair, chemicals, etc.), the millions of tiny air sacs within the lungs are constricted, seriously impairing breathing and causing a feeling of tightness in the chest. In addition to IgE-released histamine, the primary biochemical cause of the asthmatic symptoms is a group of fatty acid derivatives called leukotrienes (LTs). These asthma-causing LTs are made from arachidonic acid (a key fatty acid constituent of many cell membranes) by the action of two enzymes - phospholipase A2 and lipoxygenase. Quercetin is known to be a powerful inhibitor of both these enzymes. Thus it prevents the formation of asthma-causing LTs, even when the IgE antibody (formed in response to inhaled or swallowed allergens) is present in the lungs to stimulate LT Production and release. Since quercetin suppresses the release and/or production of the two primary inflammatory mediators–histamine and leukotrienes–that cause the actual symptoms of asthma, its potential benefit in the prevention and treatment of asthma is evident.
Quercetin is a safe, nontoxic substance. A report by I. Hirono et al in Cancer Letters (1981), for example, found no evidence of toxicity or carcinogenicity in rats, even when quercetin made up 10 percent of their total dietary intake.
Unfortunately, quercetin is barely soluble in water, so poor dietary absorption may limit its efficacy. Because of this, it has been suggested that quercetin be taken in combination with bromelain to improve its absorption. Bromelain is a natural, protein-digesting enzyme derived from pineapples. It has been used "to increase absorption of compounds, including antibiotics. Also, bromelain has powerful anti-inflammatory properties that synergize with quercetin. Bromelain inhibits several other common inflammatory mediators, including bradykinin and fibrin. It's widely used in sports medicine to reduce the pain and swelling of bruises, sprains, muscle tears, etc., for this reason.
Quercetin and Cancer
Quercetin has anti-tumor potential in laboratory studies, and has potential to be useful in various cancers including pancreatic cancer, however human trials are difficult to find.
Quercetin and viral illness
Quercetin, a naturally occurring, powerful antioxidant found in red grapes, red wine, red apples, green tea and broccoli, appears to be one of the first plant compound proven in a double-blind, randomized, placebo-controlled clinical trial to reduce susceptibility to viral illnesses. Dr. David Nieman, a professor at Appalachian State University was the researcher and presented his findings at the southeastern regional meeting of the American College of Sports Medicine in Charlotte, N.C. Participants in the study -- long-distance cyclists -- ingested 1,000 milligrams of pure quercetin, combined with vitamin C and niacin.
Nettle Leaf
In a double-blind, randomized study during the peak season for allergic rhinitis, an extract of the herb nettle leaf (Urtica dioica) was compared to a placebo. Ninety eight participants were given 1300 mg capsules of nettle leaf or placebo and were advised to take two capsules when symptoms began and continue for seven days.
Overall assessment ratings of nettle leaf were higher than placebo, and patients reported a slight reduction in symptoms of hayfever, including sneezing and itchy eyes. This is the only research study that has been conducted on nettle leaf for allergic rhinitis, however, it has a long history of traditional use for allergies.
Licorice (Glycyrrhiza glabra):
In the late 1950s, researchers determined that the action of licorice is comparable to cortisone in that it stimulates the adrenals, inhibits inflammation, and relieves symptoms of allergy, but without the harmful effects from commonly prescribed steroids. Another mechanism of licorice is to increase the half-life of cortisol (a hormone secreted by the adrenal glands), thereby increasing its anti-inflammatory action. Like angelica, licorice also contains coumarins, agents with a demonstrated ability to suppress mediator release from mast cells.
Habitual use of licorice can result in a loss of potassium, and it may be necessary to supplement the diet or increase the consumption of potassium-rich foods. Another consideration is that the habitual intake of licorice can promote the retention of sodium